Interim Guidance on Case Definitions to be Used For Investigations of Swine Influenza A (H1N1) Cases*

April 27, 2009 05:10 EDT

This document provides updated interim guidance for state and local health departments conducting investigations of human cases of swine influenza A (H1N1) virus. The following case definitions are for the purpose of investigations of suspected, probable, and confirmed cases of swine influenza A (H1N1) virus infection.
Case Definitions for Infection with Swine Influenza A (H1N1) Virus
A confirmed case of swine influenza A (H1N1) virus infection is defined as

a person with an acute febrile respiratory illness

with laboratory confirmed swine influenza A (H1N1) virus infection at CDC

by one or more of the following tests:

real-time RT-PCR
viral culture

A probable case of swine influenza A (H1N1) virus infection is defined as a person with an acute febrile respiratory illness who is:

positive for influenza A, but negative for H1 and H3 by influenza RT-PCR, or
positive for influenza A by an influenza rapid test or an influenza immunofluorescence assay (IFA) plus meets criteria for a suspected case

A suspected case of swine influenza A (H1N1) virus infection is defined as a person with acute febrile respiratory illness with onset
within 7 days of close contact with a person who is a confirmed case of swine influenza A (H1N1) virus infection, or
within 7 days of travel to community either within the United States or internationally where there are one or more confirmed swine influenza A(H1N1) cases, or resides in a community where there are one or more confirmed swine influenza cases.

Links to non-federal organizations are provided solely as a service to our users.

These links do not constitute an endorsement of these organizations or their programs by CDC or the federal government, and none should be inferred.

CDC is not responsible for the content of the individual organization Web pages found at these links.
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Page last reviewed April 27, 2009 08:30 EDT
Page last updated April 27, 2009 08:30 EDT